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Respiratory Science Equipments

  • PFT Animal Pulmonary Function Test System
PFT Animal Pulmonary Function Test System

PFT Animal Pulmonary Function Test System

  • Product description: In experiments, animals are anesthetized and undergo a tracheotomy. PFT animals pulmonary function test system can automatically analyse experimental data collected from anesthetized experimental anim
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PFT Animal Pulmonary Function Test System


    In experiments, animals are anesthetized and undergo a tracheotomy. PFT animals pulmonary function test system can automatically analyse experimental data collected from anesthetized experimental animal, including forced vital capacity related data test and determination of FEV (x) in a few minutes,  FEF (x), FVC, FRC, parameters such as FEVpef, MMEF, greatly shortens the time of traditional way of experiment and measurement parameters, making it a more comprehensive pulmonary function test system.

    PFT Animal Pulmonary Function Test System developed by TOW-Int is a system to comprehensively evaluate the respiratory functions of laboratory animals, measuring airway resistance, lung compliance, FEV, FVC, FEV0.1/FVC, FEV0.2/FVC, FEF, FRC, EF50 and other indicators. The system can be customized to be used in small and large animals like mice, rats, guinea pigs and others.

    Animal anesthesia and tracheotomy are required during experiments. The system is equipped with a ventilator, which can automatically control the breathing mode of the animals and cooperate with different pulmonary function tests.

    PFT Animal Pulmonary Function Test System is widely used in pre-clinical research of COPD, interstitial lung disease (ILD), pneumonia, pulmonary fibrosis and other diseases, drug evaluation in respiratory pharmacology research and general pharmacology research.

    According to the Boyle's Law, by testing the pressure difference between main airway resistance and bronchus, intrapleural pressure, airflow velocity in airway, and other direct physical indicators, directly reflecting physiological indicators exactly the same with human test in hospitals, it conforms not only to the widely recognized medical research study, but also applicable to first phase of clinical trial and has direct guiding significance.


Features of PFT Animal Pulmonary function Test system 

          1.  Product function: It is used for the comprehensive pulmonary function test of experimental animals, such as mice, rats, guinea pigs and rabbits.

          2.  Test method: Anesthesia followed by tracheotomy.

          3.  Tested Parameters: Comprehensive Pulmonary function analysis and parameters, such as testing for FEV(x), FEF(x), FVC, FEVpef, MMEF, Vt, F, Rl, etc within a few minutes. 

          4.  Support mechanically assisted ventilation mode and spontaneous breathing mode.

          5.  Imported transducers are adopted to guarantee the accuracy of data acquisition.

          6.  The maximum negative pressure is up to -10kPa. The negative pressure is adjustable and can be used for various animals, such as mice, rats, guinea pigs and rabbits.

          7.  Equipment quality: transparent PMMA material and aluminum alloy material for easy observation.

          8.  With animal intubation and blood collection interface, it can be used for intravenous drug administration of animals, arterial blood collection and other operations.

          9.   It can control animals to complete forced lung ventilation function test, such as forced inhalation, forced exhalation and other actions.

        10.  It can complete the measurement of forced expiration in small animals in the study of COPD and other animal models.

        11.  Analytic software supports Win7, Win8, Win10.

        12.  Smooth respiratory waveform output can be displayed in real time.

        13.  Allows adjustment of data recording period and recovery at any time.

        14.  Real-time continuous data collection, recording and storage of original data, the software can display original respiratory waveform in real time.

        15.  Data can be automatically stored in Excel format for the convenience of third-party software analysis. All graphs can also be saved.



Application of PFT Animal Pulmonary Function Test System
  1. Bronchial asthma
  2. Chronic obstructive emphysema (COPD)
  3. Pulmonary fibrosis
  4. Acute and Chronic respiratory distress syndrome (ARDS)
  5. Chronic bronchitis
  6. Acute and chronic respiratory failure
  7. The study of tracheal dilatation and excitation experiments
  8. Drug evaluation in respiratory pharmacology studies
  9. Life science research that requires Pulmonary function monitoring in small animals





Model Selection

Product Name

Model

Description

Unit

Pulmonary Function Test System

PFT-M

For Mice

Set

Pulmonary Function Test System

PFT-MR

For Mice ,Rats, and Guinea Pigs

Set

Our company can provide 3Q qualification to assist customers to qualify the system in all aspects.


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