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首页 > 产品详情 > 气体控制 > 动物低氧高氧实验

动物实验低压氧舱(恒温版)

产品型号:

ProOx-811

详细介绍:

动物实验低压氧舱用于模拟低压氧高原环境,压力可以根据需要自行设置,最高可模拟海拔高度12000米,适用于更多的鼠笼或中小型动物如犬、猴、兔、鼠等。整个实验装置由... 查看详情 >
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动物实验低压氧舱用于模拟低压氧高原环境,压力可以根据需要自行设置,最高可模拟海拔高度12000米,适用于更多的鼠笼或中小型动物如犬、猴、兔、鼠等。


整个实验装置由动物舱体、真空系统、监测及控制系统构成。设备的自动化程度高,无须专人守候,可长期持续一个月运行。


产品特点:

人性化操作

采用10英寸触摸屏,人性化界面设计,操作简便。

两种控制方式:自动、手动,断电可操控;具有传感器组件及机械表双重监测功能。设备自动化程序设计,无须专人守候,可长期持续运转。

实时显示海拔和氧分压动态变化曲线。

实验过程数据可导出csv格式保存到U盘中,在电脑中读取分析。

可根据客户实验需求,订制实验环境及配套其他相关实验设备。

配备动物低压专用水瓶,防止在负压环境中,水滴漏速过快。


操作安全放心 

配备自动换气功能,符合动物饲养规范。

提供多方位报警功能(温度、湿度、压力、氧浓度 上/下限),防止出现安全隐患。配备渐开手轮式舱门,降低因为误操作造成的伤害。

舱体采用透明厚亚克力材质,方便研究人员观察实验动物情况。

配备气体缓冲器,减小、甚至消除了细股急流气体对小动物的影响。

配备多级空气过滤器,确保动物舱内实验环境空气不会收到污染。


参数显示/功能全


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拓展及特殊定制

动物生理指标监测

可实现的监测指标:心电图、心率、体温、血压、呼吸、血氧饱和度;

呼吸代谢监控功能

采血给药功能

视频监测功能

动物低氧跑台装置

低氧强迫游泳装置

温控功能

恒温功能,温度可控制,室温-40℃;

低温功能,4℃,温度可控制,室温-4℃;

可定制其它功能


应用领域

高原医学研究、肺水肿、脑水肿、肺动脉高压等疾病研究


型号说明


名称

型号

说明

动物低压氧舱

(标准版)

ProOx-810

可以摆放2个大鼠笼/4个小鼠笼

动物低压氧舱

(恒温版)

ProOx-811

可以摆放2个大鼠笼/4个小鼠笼,同时加上恒温功能

动物低压氧舱

(大容量版)

ProOx-810L

可以摆放4个大鼠笼/8个小鼠笼(可叠加)

动物低压氧舱

(大容量版+恒温)

ProOx-811L

可以摆放4个大鼠笼/8个小鼠笼(可叠加),同时加上恒温功能

动物低压氧舱

基础款

ProOx-830

可以摆放1个大鼠笼/2个小鼠笼

动物低压氧舱-进阶款金属方舱(多功能)

ProOx-811ML

空间利用率高,可拓展性强,功能模块更丰富。







客户名单(部分)



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相关文献


[1]Ma Jinqiu,Wang Chenyun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina."Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia".[J] International Journal of Pharmaceutics,2020,591.


[2]Guijuan Chen,Kang Cheng,Yun Niu,Li Zhu,Xueting Wang."Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling".[J]. Archives of Biochemistry and Biophysics ,Volume 729,109393.


[3]Yapeng,LuPanpanChang,WangwangDing,JiangpeiBian,DanWang,XuetingWang,QianqianLuo,XiaomeiWu,LiZhu."Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells". [J]. European Journal of Pharmacology,Volume 929,2022,175137.


[4]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin ."Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner".[J]. European Journal of Pharmacology,Renal Failure, 44:1,2056-2065.


[5]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,"Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling".[J]. Biomedicine & Pharmacotherapy,Volume 156,2022,113982.


[6]Fang Zhao, Yan Meng, Yue Wang, Siqi Fan, Yu Liu,Xiangfeng Zhang, Chenyang Ran, Hongxin Wang and Meili Lu. "Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway".[J].Frontiers in Pharmacology,10.3389/fphar.2022.920977.


[7]Ma Jinqiu,Wang Chenyun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina. "Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia".[J] International Journal of Pharmaceutics,2020,591.


[8]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin ."Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner".[J]. European Journal of Pharmacology,Renal Failure, 44:1,2056-2065.


[9]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,"Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling".[J]. Biomedicine & Pharmacotherapy, Volume 156,2022,113982.


[10]Yanfei Zhang, Jinyu Fang, Yingyue Dong, Huiru Ding, Quancheng Cheng, Huaicun Liu, Guoheng Xu, Weiguang Zhang"High-Altitude Hypoxia Exposure Induces Iron Overload and Ferroptosis in Adipose Tissue."[J]. Antioxidants 2022,11,2367.


[11]Wan-ping Yang, Mei-qi Li, Jie Ding, Jia-yan Li, Gang Wu, Bao Liu, Yu-qi Gao, Guo-hua Wang, Qian-qian Luo. "High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen."[J]. bioRxiv preprint, 2023.03.23.533972.


[12]Xueting Wang,Yuqi Xie,Yun Niu,Baolan Wan, Yapeng Lu,Qianqian Luo,Li Zhu.CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting[J].2023-05-10,DOI:10.3389/fncel.2023.1189348.


[13]Liu,J,Peng,S,Ye,L,Sun,Y,Zhao, Q, Wei, H,Luo, Q, He M, & Wang, G(2023)."Neuroinflammation aggravated by traumatic brain injury at high altitude is reversed by L-serine via NFAT1-mediated microglial polarization."[J]. Frontiers in Cellular Neuroscience,17,1152392.doi: 10.3389/fncel.2023.1152392.


[14]Ru Zhang,Ailin Yang,Lin Zhang,Linjie He,Xiaoming Gu,Caiyong Yu,Zhenxing Lu,Chuang Wang, Feng Zhou,Fei Li,Lele Ji,Jinliang Xing,Haitao Guo."MFN2 deficiency promotes cardiac response to hypobaric hypoxia by reprogramming cardiomyocyte metabolism."[J]. WILEY Online Library,2023-07-04 DOI: 10.1111/apha.14018.


[15]Zhang L, Liu X, Wei Q, et al. Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p[J]. Mammalian Genome, 2023, 34(1): 76-89.


[16]Yang A, Guo L, Zhang Y, et al. MFN2-mediated mitochondrial fusion facilitates acute hypobaric hypoxia-induced cardiac dysfunction by increasing glucose catabolism and ROS production[J]. Biochimica et Biophysica Acta (BBA)-General Subjects, 2023: 130413.


[17]Wei J, Hu M, Chen X, et al. Hypobaric Hypoxia Aggravates Renal Injury by Inducing the Formation of Neutrophil Extracellular Traps through the NF-κB Signaling Pathway[J]. Current Medical Science, 2023: 1-9.


[18]Wang X, Xie Y, Niu Y, et al. CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting[J]. Frontiers in Cellular Neuroscience, 2023, 17: 1189348.


[19]Ma Q, Ma J, Cui J, et al. Oxygen enrichment protects against intestinal damage and gut microbiota disturbance in rats exposed to acute high-altitude hypoxia[J]. Frontiers in Microbiology, 2023, 14.



参考研究


高原疾病介绍


不同的海拔高度大气压和氧分压的变化对比


 


*我公司可提供3Q验证,根据客户的特殊应用、特殊需求提供功能定制服务,也可以提供相关的实验服务,详情请来电咨询。